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Redcuction of post surgery vomiting by glucose containing fluids

Does perioperative administration of 5% dextrose effective in reducing incidence of PONV in patients undergoing laparoscopic cholecystectomy: A prospective, double blind, randomized controlled study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2016/03/006697
Enrollment
100
Registered
2016-03-02
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- patients with gall stone disease undergoing laparoscopic cholecystectomy

Interventions

Intervention1: 5% Dextrose: 250 ml of 5% dextrose to be given at 100 ml/hr after removal of gall bladder Control Intervention1: sterofundin: 250 ml sterofundin is also administered after removal of ga

Sponsors

AIIMS
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.total 100 ASA I and II patients with gall stone disease posted for laparoscopic cholecystectomy. 2. patients who give written informed consent.

Exclusion criteria

Exclusion criteria: - [atient refusal -history of coronary artery disease/ congestive heart failure/ diabetes melliutus/ renal insufficiency/ severe hypertension/ peptic ulcer. -patients on anti emetics or steroids -pregnant females -patients requiring large iv fluid for intraoperative hypotension. -cancer patients on opioids

Design outcomes

Primary

MeasureTime frame
1. to assess the efficacy of administration of 5% dextrose perioperatively in reducing the incidence of PONV in patients undergoing laparoscopic cholecystectomy. 2. to see the difference in consumption of rescue antiemetics to combat PONV in postoperative period in two groups taken up for study.Timepoint: to be followed upto 24 hours postoperatively

Secondary

MeasureTime frame
to assess the relationship of 5% dextrose administration with incidence of PONV in patients with high and low Apfel scores.Timepoint: retrospective analysis

Countries

India

Contacts

Public ContactDr Ankita Mishra

AIIMS

ankita02091987@gmail.com9716811848

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026