Health Condition 1: null- ASA status I to II patients undergoing post traumatic long bone surgeries of femur and tibia
Conditions
Interventions
Intervention1: Group PE: This group will receive preemptive multimodal pharmacologic agents
Intravenous diclofenac 75 mg, intravenous morphine 3mg, 1gm of intravenous acetaminophen and 75mg pregabalin per orally one hour before the start of surgery
Control Intervention1: Group C: Will not re
Sponsors
Post Graduate Institute Of Medical Education Research
Eligibility
Inclusion criteria
Inclusion criteria: Patients undergoing post traumatic long bone surgeries of femur and tibia.
Exclusion criteria
Exclusion criteria: History of associated head injury, blunt trauma abdomen or blunt trauma chest 2) allergy and contraindications to any of the medications being used 3) history of being on chronic pain medications (i.e. slow-release preparations of opioids) 4) rheumatoid arthritis 4)psychiatric disorder 5) a history of diabetes with impaired renal function 6) morbid obese 7) patients unable or unwilling to use patient-controlled epidural analgesia (PCEA). (8) prior use of the investigated medications (9) current use of anticoagulants or antiplatelet medication
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Mean number of boluses of PCA or PCEATimepoint: At 24 and 48 hrs | — |
Secondary
| Measure | Time frame |
|---|---|
| Mean VAS scores in post operative period Postoperative nausea, vomiting, sedation scoresTimepoint: 30 min, 1 hr, 2 hrs, 4hrs, 8hrs, 12 and 24 hrs and on postoperative day 2. | — |
Countries
India
Contacts
Public ContactJeetinder kaur
POST GRADUATE INSTITUTE OF MEDICAL EDUCATION AND RESEARCH
Outcome results
None listed