To Study the Effect of Plant Formulation on sleep in Patients with Depression.

Assesment of Neuropsychopharmacological action of Polyherbal formulation in association with regulation of Biomarkers and sleep pattern in Mild to Moderate Depressed patients. - Sleep, Melatonin and Depression

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2016/02/006681

Enrollment

Registered

2016-02-25

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Depressive symptoms with cognitive impairment, Sleep Disturbances

Interventions

Intervention1: A Polyherbal Formulation: The composition consists of Bacopa monneri - 225 mg Discorea bulbifera - 125 mg Hippophae Rhamnoids- 125mg Additives 25 mg (CaCO3), Duration 6 months. Co

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients with age between 30 - 65 years (Both genders) 2. Patient health questionnaire (PHQ-9) scores 5-14 3. Hamilton depression rating scale score 19-22. 4.Patient must meet the DSM-V Criteria for Depression. Patients willing to give informed consent.

Exclusion criteria

Exclusion criteria:

Design outcomes

Primary

Measure	Time frame
Sleep Efficiency, REM Sleep, Melatonin & Neopterin levelsTimepoint: visit 3, visit 6	—

Secondary

Measure	Time frame
Improvement of Cognitive, Memory status, Neopterin levels.Timepoint: NA	—

Countries

India

Contacts

Public ContactProfGPDubey

SRM University

ayursatish@gmail.com9884845887

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026