Health Condition 1: null- ASA physical status 1-3 patients undergoing unilateral total knee replacement surgery
Conditions
Interventions
Intervention1: Total intravenous anaesthesia: total intravenous general anaesthesia with propofol and fentanyl infusion and local infiltration at the end of surgery with a 40ml solution of 0.5% ropiv
Sponsors
All India Institute of Medical Sciences
Prof Anjan Trikha
Eligibility
Inclusion criteria
Inclusion criteria: Patients willing to undergo elective, primary, unilateral total knee arthroplasty under general or spinal anaesthesia, with age 18 â?? 85 years and belonging to American Society of Anesthesiologists Physical Status (ASA PS) I â?? III
Exclusion criteria
Exclusion criteria: 1. Patientâ??s refusal to take part in the study 2. Bilateral / Revision total knee arthroplasty 3. Morbid obesity (BMI >= 40 ) 4. History of allergy to the drugs used in the study 5. History of regular opioid use 6. Contraindications to spinal anesthesia 7. Inability to understand information regarding Visual Analogue Scale 8. Inability to understand the use of patient controlled analgesia device
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1. Time to readiness for discharge as measured by the proportion of patients in each group meeting the discharge readiness criteria on subsequent postoperative days, with assessment starting from day 2 onwardsTimepoint: Everyday from postoperative day 2 onwards till discharge criteria is met | — |
Secondary
| Measure | Time frame |
|---|---|
| postoperative opioid consumption and postoperative recovery profile - postoperative pain, urinary retention, nausea and vomitingTimepoint: first 24 hours postoperatively | — |
Countries
India
Contacts
Public ContactDr Bharathram V
All India Institute of Medical Sciences
Outcome results
None listed