Is reversal of muscle paralysis necessary after giving blocking drugs?

Neostigmine reversal of atracurium induced neuromuscular blockade in daycare paediatric cases - Is it necessary?

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2016/01/006553

Enrollment

100

Registered

2016-01-22

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA I - II paediatric patients undergoing daycare infraumblical surgery

Interventions

Intervention1: Neostigmine group: After randomization, all patients will recieve standard anaesthesia care.TOF -watch (FDA approved neuromuscular monitor) is calibrated before giving atracurium 0.5mg/

Eligibility

Inclusion criteria

Inclusion criteria: ASA class I - II scheduled to undergo infraumblical surgery of less than 120 minutes duration on daycare basis

Exclusion criteria

Exclusion criteria: parent/guardian refusal, ASA class III-IV, Any history of neuromuscular weakness, a positive history of respiratory illness

Design outcomes

Primary

Measure	Time frame
Residual neuromuscular block (TOF 0.9)Timepoint: before shifting the patient from OT after the surgery	—

Secondary

Measure	Time frame
hypoxemia (95%) upper airway obstruction coughing laryngospasm bronchospasm need for airway assisstance flushing nausea and vomitingTimepoint: upto 6 hours postoperatively	—

Countries

India

Contacts

Public ContactDr Deepanjali Pant

Sir Ganga Ram Hospital

deepanjalipant@gmail.com09818271871

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026