Health Condition 1: null- PATIENTS ARE EITHER A COMPLETE HEALTHY (ASA-I) OR HAVE MILD SYSTEMIC DISEASE (ASA-II)
Conditions
Interventions
Intervention1: DEXMEDETOMIDINE OR KETAMINE: After inducing general anaesthesia with intravenous fentanyl 2 µg/kg, intravenous propofol 2-3 mg/kg and intravenous rocuronium 1 mg/kg, maintenance of ana
Sponsors
All India Institute Of Medical Sciences
Eligibility
Inclusion criteria
Inclusion criteria: Any patient male or female aged 18-60 years of age scheduled for elective lumbar instrumentation surgery.
Exclusion criteria
Exclusion criteria: - Intolerance or known allergy to ketamine or dexmedetomidine - History of liver or renal disease - Patients who are on chronic β-blocker treatments with low baseline heart rate ( - Pregnant patients - Increased intra-ocular pressure - Uncontrolled hypertension - Increased intracranial pressure - History of psychosis, seizure disorder - ASA- III or IV
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To compare the difference in post-operative analgesic requirements in between the groupsTimepoint: 1st 24hours after surgery | — |
Secondary
| Measure | Time frame |
|---|---|
| 1)Intraoperative anesthetic requirements 2)To compare the intraoperative hemodynamics such as heart rate (HR) and mean arterial pressure (MAP) 3)To compare the post operative side effects of the 2 agents in 1st 24 hours after surgery. 4)Duration of ICU and hospital stay Timepoint: mentioned in outcome | — |
Countries
India
Contacts
Public ContactRANADHIR MITRA
A.I.I.M.S (all india institute of medical sciences)
Outcome results
None listed