Health Condition 1: null- Low back pain with unilateral radicular component
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: • Low back pain with unilateral lumbosacral radicular pain (sharp, shooting or lacanting pain perceived in skin and deep) for at least 3 month duration not responding to medication and physical therapies • BMD T score of more than â?? 1.0 SD of the total hip and spine. • Evidence of magnetic resonance imaging (MRI) of disc herniation at 1-2 levels.
Exclusion criteria
Exclusion criteria: Patient with history of surgery on lumbar Spine, Spinal canal stenosis, spondylolisthesis Allergic to contrast or steroid . Bleeding diathesis, Patient who received lumbar epidural steroid injection in past six months or using systemic steroid for pain relief Pregnant patients History of disease known to affect bone turnover, Documentation of abnormal serum thyrotropin levels, high parathyroid hormone levels, or using drugs known to affect bone metabolism, History of intake of oral, parenteral, or inhaled glucocorticoids for more than 4 weeks or an intra-articular injection in the preceding year.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Primary aim of our study will be the incidence of patients achieving effective pain relief(defined as decrease in VAS score by 50%)Timepoint: Primary aim of our study will be the incidence of patients achieving effective pain relief(defined as decrease in VAS score by 50%) | — |
Secondary
| Measure | Time frame |
|---|---|
| Contrast spread pattern Overall VAS scores Number of injections required Bone marrow density- Baseline and 3months Serum calcium levels, vit D3 levels S Osteocalcin levels Timepoint: Baseline and 3 months | — |
Countries
India
Contacts
PGIMER