CBT for Obsessive compulsive disorder

Cognitive behaviour therapy for partial responders with OCD: A randomized controlled trial - CBT

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2016/01/006479

Enrollment

Registered

2016-01-04

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: F422- Mixed obsessional thoughts and acts Health Condition 2: null- Obsessive Compulsive Disorder

Interventions

Intervention1: Cognitive Behaviour therapy and Risperidone (antipsychotic augmentation): Eligible participants fulfilling the criteria for at least partial response to SRIs will be randomized to one o

Simpson et al., 2008). Those in the CBT group will receive risperidone pill placebo to mask the effect of risperidone. Control Intervention1: Antipsychotic augmentation (risperidone): patients receivi

Eligibility

Inclusion criteria

Inclusion criteria: 1. Patients fulfilling the criteria for primary diagnosis of Obsessive Compulsive Disorder according to DSM-IV. (300.3). 2. Age-18 â??50 years. 3.Patient with both obsessions and compulsions (Mixed subtype of OCD). Partial treatment response to adequate trial with at least one of the SRIs. Y â?? BOCS Symptom severity score of 16 and above. 4. Symptom duration of at least 1 year. 5. Stabilized on medications for at least 4 weeks prior to recruitment.

Exclusion criteria

Exclusion criteria: 1. A primary diagnosis of schizophrenia, bipolar affective disorder, severe depression, mental retardation, epilepsy, head injury or other neurological disorders. 2. Substance use, dependence, excepting Nicotine dependence in the past 6 months prior to recruitment. 3. Previous exposure to structured cognitive behaviour therapy for obsessive-compulsive disorder (15 sessions or more of CBT comprising of exposure and response prevention) in the last 6 months. 4. Symptom duration greater than 15 years. 5. Pregnancy, nursing or any other unstable medical condition

Design outcomes

Primary

Measure	Time frame
Symptom severity on Yale Brown obsessive compulsive scale YBOCS- at baseline mid and post therapy CGI-Scale (improvement) at post therapy at post therapyTimepoint: Yale Brown obsessive compulsive scale YBOCS- at baseline- mid therapy CGI-Scale (improvement) at mid and post therapy	—

Secondary

Measure	Time frame
HAMD (depression)HARS, (anxiety), functioning, Quality of lifeTimepoint: Baseline, post and follow-up	—

Countries

India

Contacts

Public ContactPaulomi Sudhir

NIMHANS

paulomi.sudhir@gmail.com918026995184

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026