Health Condition 1: null- Paediatric patients for gastrointestinal endoscopies
Conditions
Interventions
Intervention1: Sevoflurane: Sevoflurane at 4% dial concentration in O2:N2O mixture(50:50) to begin with, followed by mixture of O2 in sevoflurane at 1-2% dial concentration for sedation during gastroi
Sponsors
Vanya Chugh
Eligibility
Inclusion criteria
Inclusion criteria: Patients undergoing elective upper or lower GI endoscopic procedures. American Society of Anaesthesiologists class I & II (I: healthy; II: single, controlled disease state). Parents and guardians of the patient consenting for the procedure.
Exclusion criteria
Exclusion criteria: a. American Society of Anaesthesiologists class III and above. b. Known hypersensitivity to propofol or ketamine or sevoflurane or h/s/o egg allergy. c. Patients with following conditions: i. Airway related problems. ii. Respiratory disorders. iii. Cardiovascular disorders. iv. Central nervous system disorders/neurologic impairment. v. Acute febrile illness. vi. Bleeding oesophageal varices. d. History of recent hepatitis e. Renal insufficiency
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to emergence from procedural sedation Timepoint: 1) Emergence time - From end of procedure till achievement of Modified Ramsay Sedation Score â?¤ 3. 2) Time to respond to light painful stimulus 3) Time to cough 4) Time to spontaneous eye opening 5) Time to achievement of purposeful limb movements 6) Time to child becoming oriented (older children) | — |
Secondary
| Measure | Time frame |
|---|---|
| 1) Effectiveness of sedation in terms of Induction time, success of Induction, success of maintenance 2) Safety in terms of occurrence of complicationsTimepoint: â?¢Induction time: Administration of study drugs to fixation of eyeballs, adequate jaw relaxation and Modified Ramsay Sedation Score 4 or 5. â?¢Success of Induction: Induction doses sufficient to allow easy passage of endoscope. Need of changeover from one group to the other will be considered as failure. â?¢Success of maintenance: Maintenance doses sufficient to carry out the procedure. Need of changeover from one group to the other will be considered as failure. | — |
Countries
India
Contacts
Public Contactvanya chugh
Lokmanya Tilak Municipal Medical College and General Hospital
Outcome results
None listed