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Effect of two different doses of Anaesthesia regimen on Fertility rates during Ovum pickup under General Anaesthesia

EFFECT OF TWO ANAESTHETIC PROPOFOL REGIMEN ON FERTILITY RATES DURING ULTRASOUND GUIDED TRANSVAGINAL OOCYTE RETRIEVAL FOR INVITRO FERTILISATION-EMBRYO TRANSFER (IVF - ET) A RANDOMISED CONTROLLED TRIAL

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/12/006411
Enrollment
40
Registered
2015-12-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Individuals with Primary Infertility scheduled for ULTRASOUND GUIDED TRANSVAGINAL OOCYTE RETRIEVAL FOR INVITRO FERTILISATION-EMBRYO TRANSFER (IVF - ET)

Interventions

Intervention1: Propofol as intermittent bolus for Anesthesia: b) Group B (Continuous Infusion group) 1. Preoxygenation (Tidal volume breathing for 2 min using 100% Oxygen@6 lit/min with Bains circuit

Sponsors

Armed Forces Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: a) Registered with ARTC for Infertility therapy b) Primary Infertility c) Patients in ASA 1 Physical status category for Anaesthesia d) Age e) Planned to undergo IVF-ET as per protocol

Exclusion criteria

Exclusion criteria: a) Male factor / Female factor infertility b) Obesity (BMI > 30 kg/m2) c) History of Allergy to any of the study medication d) Undergoing Intracytoplasmic Sperm Insemination (ICSI) e) Included in any other research / study protocol

Design outcomes

Primary

MeasureTime frame
Chemical pregnancy by Serum Beta HCG levelsTimepoint: Chemical pregnancy by Serum Beta HCG levels—

Secondary

MeasureTime frame
1. Total Propofol administered (mg) 2. Total Propofol administered (mg/kg body weight) 3. Total IV Fluids administered (ml) 4. Total IV Fluids administered (ml/kg body weight) 5. Procedure time (Probe insertion to removal at end of procedure) (seconds) 6. Exposure time (Induction to Removal of probe) (seconds) 7. Recovery time (Removal of probe to Recovery by Eye opening to verbal command) (seconds) Timepoint: Under Anaesthesia;2. Fertilisation rate (Total Pronuclear (PN) stage cells / Total number of oocytes fertilised)Timepoint: Day 2,3 and 5 of Ovum pickup—

Countries

India

Contacts

Public ContactDr Col Mathews Jacob

AFMC

bhargavadv@rediffmail.com8135855155

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026