Health Condition 1: null- Pregnant women between 28-34 weeks of gestational age, before preterm birth
Conditions
Interventions
Intervention1: natural bovine surfactant: 3 ml of natural bovine surfactant given. Each ml contains 27 ml phospholipids and 176-500 mcg of surfactant associated proteins SP-B and SP-C
Control Interven
Sponsors
Project under thesis at All India Institute of Medical Sciences New Delhi
Eligibility
Inclusion criteria
Inclusion criteria: Pregnant women at 28-34 weeks of gestational age, in preterm labour or before preterm caesarean section
Exclusion criteria
Exclusion criteria: Preterm premature rupture of membranes, chorioamnionitis, congenital fetal malformations, positive foam stability test (for lung maturity) in amniotic fluid
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of respiratory distress syndrome (RDS),severity of RDS, need of postnatal intra-tracheal surfactantTimepoint: Outcome was assessed at the time of delivery and till discharge of baby from nursery | — |
Secondary
| Measure | Time frame |
|---|---|
| APGAR score (at 1 and 5 minutes after birth), foam stability test of gastric lavage, FiO2 requirement of CPAP and its duration, need of mechanical ventilation and its duration, length of hospital stayTimepoint: once | — |
Countries
India
Contacts
Public ContactNutan Agarwal
All India Institute of Medical Sciences, New Delhi
Outcome results
None listed