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A study comparing the effect of Hepatic Artery Flushing with cold Preservative solution in Liver Transplant.

A Randomized control trial comparing the impact of Hepatic Artery and Portal Vein flushing versus Portal Vein flushing alone in Live Donor Liver Transplant patients, on the immediate and long term graft function. - HALT

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/11/006398
Enrollment
60
Registered
2015-11-30
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients suffering from Chronic Liver Disease who require Liver Transplant for survival.

Interventions

Intervention1: Hepatic Artery Perfusion and Portal Vein Perfusion: In addition to pefusion/flushing of the Portal Vein of the graft liver during the backtable preparation, the Hepatic Artery will also

Sponsors

Amrita Institute Of Medical Sciences
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All consenting patients undergoing Live Donor Liver Transplantation.

Exclusion criteria

Exclusion criteria: ABO Incompatible Liver Transplants.

Design outcomes

Primary

MeasureTime frame
Early and late biliary complications. 1. Biliary Leak 2. Biliary StrictureTimepoint: Post operative period to the last follow up date.

Secondary

MeasureTime frame
Intra operative Haemodynamic parameters - The parameters of intra-operative hemodynamic changes measured includes the measurement of Post Reperfusion Syndrome.Timepoint: Intra operative;Length of post-operative hospital stay.Timepoint: Total Hospital stay;Liver Function Tests measured immediately post-transplant and on the Post Op Day 1, Day 3, Day 7, Day 14 and 1 month.Timepoint: Post operative days as mentioned;Post-operative graft and patient survival rates.Timepoint: Long term graft and patient survival figures up to the last follow up.;Vascular Complications â?? vascular complications includes stenosis or occlusion of the anastomoses of the Hepatic artery, Portal vein and Hepatic vein which required surgical or radiological interventions or has been demonstrated by any imaging modality.Timepoint: In the post operative period.

Countries

India

Contacts

Public ContactDr Johns Shaji Mathew

Amrita Institute Of Medical Sciences

johnssm20981@aims.amrita.edu9447348629

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026