Health Condition 1: null- Pyogenic Meningitis
Conditions
Interventions
Intervention1: Dexamethasone: 0.15mg/kg/dose QDS for initial 4 days of antibiotic therapy. 1st dose of dexamethasone to be given 15 minutes before 1st dose of antibiotic
Control Intervention1: Normal
Sponsors
Kolkata Medical College and Hospital
Eligibility
Inclusion criteria
Inclusion criteria: 1. Any patient of 6 months to 12years of age with clinical manifestations of acute meningitis, CSF profile consistent with bacterial meningitis. 2. Confirmed pathogen by blood or CSF culture.
Exclusion criteria
Exclusion criteria: 1 Patientâ??s age less than 6 months or more than 12years. 2 Where CSF analysis is not done or CSF profiles were not compatible with bacterial meningitis are to be excluded. 3 Neonatal maninigitis . 4 Patients received antibiotics outside before admission. 5 CSF suggestive of viral, tubercular or fungal etiology. 6 any patient with a congenital or acquired abnormality of the central nervous system 7 a prosthetic device inserted into the central nervous system 8 previous episodes of bacterial meningitis 9 an underlying neurologic abnormality 10 a history of hypersensitivity to beta-lactam antibiotics are excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MortalityTimepoint: 3weeks | — |
Secondary
| Measure | Time frame |
|---|---|
| Developement of seizure disorderTimepoint: 3months;Hearing impairmentTimepoint: 6months | — |
Countries
India
Contacts
Public ContactDebajyoti Datta
Medical college and hospital, kolkata
Outcome results
None listed