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Additional injection to prevent infection after cesearean delivery

Randomized double blinded controlled trial to compare the efficacy of Extended spectrum antibiotics with narrow spectrum antibiotic as prophylaxis in Cesarean delivery for the prevention of post Cesarean endometritis. - PACS

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/10/006329
Enrollment
1996
Registered
2015-10-29
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: O00-O9A- Pregnancy, childbirth and the puerperium Health Condition 2: null- Pregnant women completed 37 weeks undergoing cesarean section

Interventions

Intervention1: injection azithromycin 500 mg in 250ml NS intravenous single dose over 1 hr: injection azithromycin 500 mg in 250ml NS intravenoue over 1 hr single dose with injection cefazolin 1 gm i

Sponsors

internal fluid research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: pregnant women with completed 37 weeks undergoing cesarean section

Exclusion criteria

Exclusion criteria: Patients with known allergy to Cephalosporin and Azithromycin Patient who have received antibiotics within a week prior to the delivery or intrapartum propylaxis for chorioamnionitis.

Design outcomes

Primary

MeasureTime frame
endometritis until 42days post operative surgical site infection until 42days postoperative urinary tract infection until 42days postoperative length of hospital stay attributed to mothers illness .At the end of 42 days postoperative ,patient will reassedTimepoint: endometritis until 42days post operative surgical site infection until 42days postoperative urinary tract infection until 42days postoperative length of hospital stay attributed to mothers illness .At the end of 42 days postoperative ,patient will reassed

Secondary

MeasureTime frame
anaphylactic reactions number of readmisions until 6 weeks postoperative maternal death due to sepsis or other causes until 6 weeks postoperativeTimepoint: 6 weeks postoperative

Countries

India

Contacts

Public ContactDrSivasankari

Christian medical college

rubyjose1@gmail.com04162286185

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026