Pain relief after chest surgery

A randomized evaluation of intercostal block as an adjunct to epidural analgesia for post-thoracotomy pain

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2015/10/006283

Enrollment

120

Registered

2015-10-20

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- undergoing postero-lateral thoracotomy for tumours of the thoracic cavity

Interventions

Intervention1: Intercostal block group: Intercostal block with 0.25% bupivacine on four intercostal nerves, each of the two nerves above and below the level of thoracotomy, with 2 ml per nerve using a

Eligibility

Inclusion criteria

Inclusion criteria: ASA grade I, II and III patients undergoing standard posterolateral thoracotomy

Exclusion criteria

Exclusion criteria: 1. Refusal of consent 2. Contra-indication to epidural 3. Contra-indication to any of the study drugs (lignocaine, bupivacaine, fentanyl, diclofenac, paracetamol) 4. Additional surgical incisions during the same sitting (except mediastinoscopy) 5. Previous thoracotomy/ thoracoscopy 6. Use of pain medications in the pre-operative period

Design outcomes

Primary

Measure	Time frame
Pain score Timepoint: 2 to 4 hours after surgery	—

Secondary

Measure	Time frame
Analgesic requirementsTimepoint: first 24 hours after surgery;Maximum volume achieved on spirometryTimepoint: 18 to 24 hours after surgery;Pain scoreTimepoint: 18 to 24 hours after surgery	—

Countries

India

Contacts

Public ContactPriya Ranganathan

Tata Memorial Hospital, Mumbai

asharab@gmail.com91-22-24177000

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026