Health Condition 1: null- Suspected sepsis or any condition warranting CSF study
Conditions
Interventions
Intervention1: sitting,placebo: 1 gm of placebo to be applied
Route- on skin over lumbar area
Duration- for 1 hour under tight occlusion.
Dosage-1gm to be applied once per baby in a 48 hour period
Sponsors
Sir Ganga Ram Hospital
Eligibility
Inclusion criteria
Inclusion criteria: All neonates admitted in NICU who are planned to undergo lumbar puncture as decided by the treating physician.
Exclusion criteria
Exclusion criteria: Intraventricular hemorrhage Mechanical ventilation Neonatal encephalopathy Congenital anomaly Neural tube defects vertebral defects Other gross congenital anomalies Local skin inflammation or infection or exudative skin lesion. Cardiovascular instability Surgery in preceding 7 days Received muscle relaxants, sedatives & analgesia during previous 24 hours Failure to obtain consent
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| 1.Physiological parameters: heart rate, transcutaneous oxygen saturation and PCO2 2.Pain scores assessed as per PIPP score 3.Occurrence of adverse skin reaction like blanching, rashes, erythema, purpuric lesion at site of application 4.Number of attempts taken for successful lumbar punctureTimepoint: 24 hour after end of procedure | — |
Primary
| Measure | Time frame |
|---|---|
| Successful lumbar puncture defined as obtaining a non-hemorrhagic CSF (grossly clear CSF and/or CSF RBC count 1000/mm3)Timepoint: immediately at end of lumbar puncture- 0 min at end of lumbar puncture | — |
Countries
India
Contacts
Public ContactDr Susanta Kumar Badatya
Sir Ganga ram Hospital
Outcome results
None listed