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To study the medicinal effectiveness of SafÅ«f Hajar-al YahÅ«d in patients of HasÄ?h al-Kulya (Nephrolithiasis).

Anti-nephrolithic potential of SafÅ«f Hajar-al YahÅ«d (Unani Pharmacopeial Formulation) in patients of HasÄ?h al-Kulya (Nephrolithiasis)

Status
Recruiting
Phases
Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/10/006276
Enrollment
30
Registered
2015-10-19
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: N200- Calculus of kidney Health Condition 2: null- HasÄ?h al-Kulya (Nephrolithiasis)

Interventions

Intervention1: Safūf Hajar-al Yahūd: 5g, BD Orally, with water after meals for a period of 8 weeks Control Intervention1: NIL: NA

Sponsors

Central Council for Research in Unani Medicine CCRUM New Delhi
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with HasÄ?h al-Kulya (nephrolithiasis) as diagnosed by X-Ray/Ultrasound KUB with calculi measuring between 3 to 6 mm with or without any of the following symptoms: • Bawl al-Dam (Haematuria) • Siqlâ?? al-Khasira (Heaviness in the Loin) • Wajaâ?? al-Khasira (Pain in the Loin) • History of Recurrent UTI • History of Recurrence of Renal Stone • Urine showing Calcium Crystaluria

Exclusion criteria

Exclusion criteria: • Patients having acute condition of nephrolithiasis • Complicated cases of nephrolithiasis requiring surgical intervention • Patients with hydronephrosis, acute symptoms of UTI or any other renal diseases • Patients with serum creatinine > 2mg% • Patients on long-term medications • Patients with cardiac, pulmonary or hepatic diseases • Pregnancy and lactation • Alcohol or drug abuse/ History of alcohol or drug abuse within 6 months prior to baseline

Design outcomes

Primary

MeasureTime frame
Anti-nephrolithic potential of Safūf Hajar-al Yahūd by using osteopontin, oxidative stress markers (Glutathione, Malondialdehyde, Superoxide dismutase) and electrolytes (Sodium, Potassium, Calcium, Phosphorous, Magnesium, Chloride).Timepoint: 8 WEEKS

Secondary

MeasureTime frame
This study will help us to observe the role of osteopontin, oxidative stress markers and electrolytes in HasÄ?h al-Kulya (Nephrolithiasis).Timepoint: 8 WEEKS

Countries

India

Contacts

Public ContactDr Pradeep Kumar

Central Council for Research in Unani Medicine (CCRUM)

ccrum507@gmail.com9810161758

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026