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THE ROLE OF METHYLENE BLUE IN PREVENTION OF FALL IN BLOOD PRESSURE DURING SURGERY FOR PERFORATION OF BOWEL

THE EFFECT OF METHYLENE BLUE ON HEMODYNAMIC CHANGES WITH ANAESTHETIC INDUCTION IN PATIENTS WITH PERFORATION PERITONITIS

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/10/006256
Enrollment
30
Registered
2015-10-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with perforation peritonitis

Interventions

Intervention1: METHYLENE BLUE: Increases blood pressure Intervention2: Methylene blue (10%): Patients in Study group were given 2mg/kg of Methylene blue(10%), diluted to 50 cc, was infused intravenous

Sponsors

JAWAHARLAL INSTITUTE OF POSTGRADUATE MEDICAL EDUCATION AND RESEARCH
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients with perforation peritonitis posted for laparatomy

Exclusion criteria

Exclusion criteria: Renal dysfunction Liver dysfunction Anti psychiatric drugs Allergy to methylene blue

Design outcomes

Primary

MeasureTime frame
Mean arterial pressure Cardiac output Systemic vascular resistance Inotropic requirementTimepoint: pre induction Every 5 min post induction till 60 min—

Secondary

MeasureTime frame
Inotrope requirement Ventilator daysTimepoint: Intraoperative period Post operative day 7—

Countries

India

Contacts

Public ContactSenthilnathan M

JIPMER

anushacherian@gmail.com9789197801

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026