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Effect of phenylepherine on spinal block for cesarean section.

Effect of intravenous phenylepherine infusion on the ED50 of intrathecal plain bupivacaine with fentanyl for cesarean section

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/10/006242
Enrollment
36
Registered
2015-10-06
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- pregnant patients undergoing LSCS Health Condition 2: O94- Sequelae of complication of pregnancy, childbirth, and the puerperium

Interventions

Intervention1: Infusion: Prophylactic infusion of phenylepherine to prevent post spinal hypotension during LSCS Control Intervention1: infusion: Therapeutic bolus of phenylepherin to treat post spinal

Sponsors

University College of Medical Sciences and GTB Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status I or II and an uncomplicated singleton pregnancy of 37 weeks or greater gestation undergoing elective LSCS will be included.

Exclusion criteria

Exclusion criteria: Patients with extremes of height or weight (body mass index 35 kg/m2, height 180 cm),those who refuse consent, or with pregnancy induced hypertension, history of diabetes mellitus, cardiovascular or cerebrovascular diseases, fetal abnormalities or any contraindication to combined spinal epidural block will also be excluded.

Design outcomes

Primary

MeasureTime frame
The dose of intrathecal plain bupivacaineTimepoint: After Sub-arachnoid block, the spinal block both sensory and motor characteristics will be assessed at every 3 minutes for 15 minutes for adequacy of intrathecal dose

Secondary

MeasureTime frame
Umbilical artery pH and Apgar scoringTimepoint: Umbilical Artery pH at birth. Apgar scoring at birth and 5 minutes after birth

Countries

India

Contacts

Public ContactDr Aanchal Kakkar

University College of Medical Sciences and GTB Hospital

kakkaraanchal2@gmail.com9899368080

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026