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To assess B.P.& H.R.intraoperatively during laparoscopic cholecystectomy using either I.V Clonidine or I.V. Fentanyl

Randomized controlled trial to study the effect of I.V. clonidine and I.V. fentanyl on perioperative hemodynamics during laparoscopic cholecystectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/09/006154
Enrollment
80
Registered
2015-09-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- American society of anaesthesiologist grade I and II

Interventions

Intervention1: CLONIDINE: Central alpha 2 agonist,I.V...2mcg/kg,Frequency: Single,at the time of induction Control Intervention1: FENTANYL: Opioid,I.V., 2mcg/kg, Frequency: single at time of induction

Sponsors

Lady Hardinge Medical College
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: posted for elective laparoscopic cholecystectomy

Exclusion criteria

Exclusion criteria: • Difficult intubation ( MPG III/IV) • Emergency surgical procedures • BMI >30 • Severe Systemic disease • H/o allergy to drugs

Design outcomes

Primary

MeasureTime frame
Heart Rate,Mean Blood PressureTimepoint: baseline,before induction,before intubation,at laryngoscopy,after intubation(1min,3min,5min,10min,15min,20min,35min,50min,65min,80min,95min)—

Secondary

MeasureTime frame
rescue analgesiaTimepoint: time from drug administered till first rescue analgesic required;SevoMACTimepoint: after intubation(15min,20min,35min,50min,65min);side effects(sedation,nausea &vomiting,shivering)Timepoint: postoperative period;thiopentone doseTimepoint: before induction—

Countries

India

Contacts

Public ContactVibhor Gupta

Lady Hardinge Medical College

lhmcanaesthesia@gmail.com01123365793

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026