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comparison between dexamethasone and dexmedetomidine as an adjunct to ropivacaine in post operative shoulder surgery

A randomised double blind study comparing dexmedetomidine with dexamethasone as an adjunct to ropivacaine in ultrasound guided interscalene block for shoulder surgery

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/08/006124
Enrollment
60
Registered
2015-08-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- healthy patients with ASA grade 1-2

Interventions

Intervention1: group 1: ultrasound guided interscalene block with .5 % ropivacaine 20 ml containing dexamethasone ( 8 mg ) to a total of 22 ml Control Intervention1: group 2: ultrasound guided intersc

Sponsors

Government Medical College and Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. ASA status 1-2 2. BMI - 18-30 kg/m2 3. Shoulder surgery such as rotator cuff repair, recurrent shoulder dislocations, acromioplasty, hemiarthroplasty and total shoulder replacement.

Exclusion criteria

Exclusion criteria: 1. patient refusing to give informed consent 2. history of relevant drug allergy 3. history of psychiatric illness, substance abuse 4. severe cardiovascular, respiratory, metabolic or neurologic disease 5. pregnancy and lactation 6. coagulopathy 7. contralateral phrenic nerve dysfunction 8. infection at planned injection site 9.patients receiving alpha 2 agonists for hypertensive disorders 10.patients on steroids

Design outcomes

Primary

MeasureTime frame
duration of post-operative analgesia as measured ( in minutes ) by the time from the achievement of adequate sensory block till the first use of fentanyl bolus by PCATimepoint: o hour- time at which adequate sensory block is achieved To time till the patient takes first dose of rescue analgesic( in 24 hours )

Secondary

MeasureTime frame
pain ratings over 24 hours on 0-100 VAS , total post-operative analgesic consumption, patient satisfaction and adverse effects.Timepoint: 2 hourly monitoring after 4 hours of nerve block upto 24 hours .

Countries

India

Contacts

Public ContactDr Sukanya Mitra

Government Medical College and Hospital, Sector 32, Chandigarh.

drsmitra12@yahoo.com9646121521

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026