Health Condition 1: null- Cancer patients aged 18 to 70 undergoing major hepatobiliarysurgeries (whipples surgery, left hepatectomy and radical cholecystectomy).
Conditions
Interventions
Intervention1: Plasmalyte A: Non lactate containing intravenous fluid through intravenous line from the beginning of surgery, during intraoperative period and till 4 hrs after completion of surgery as
Sponsors
Tata Memorial Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Cancer patients undergoing major hepatobiliary surgeries
Exclusion criteria
Exclusion criteria: 1. Refusal to consent. 2. Patients who had undergone previous hepatic surgeries. 3. Chronic alcoholics. 4. Acute or Chronic hepatitis. 5. Elevated liver function tests more than twice than that of normal range. 6. Serum bilirubin >2 mg% 7. Age group less than 18 years and above 65 years. 8. Emergency surgeries. 9. Pregnant patients. 10. Patients likely to suffer massive blood loss and posted for extended hepatic resection. 11. Patients with cholangitis OR in sepsis.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The mean blood lactate levels and base deficit at 24 hours post-operatively of the patients undergoing major hepatobiliary surgeries.Timepoint: The mean blood lactate levels and base deficit at 24 hours post-operatively of the patients undergoing major hepatobiliary surgeries. | — |
Secondary
| Measure | Time frame |
|---|---|
| The mean change in arterial pH, serum electrolytes (sodium, potassium and ionic calcium) at 4 hrs and 24. hrs post-operativelyTimepoint: 24 hours from the start of the surgery | — |
Countries
India
Contacts
Public ContactDr JV Divatia
Tata Memorial Hopsital
Outcome results
None listed