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A clinical trail to study the effects of three different desensitising toothpastes on dental hypersensitivity

EFFICACY OF DESENSITIZING DENTIFRICES ON DENTINAL HYPERSENSITIVITY: A RANDOMIZED CLINICAL TRAIL

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/08/006091
Enrollment
60
Registered
2015-08-13
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Intervention1: Novamin : Calcium sodium phosphosilicate, used in the form of tooth paste, twice daily for 12 weeks Intervention2: Amine Fluoride: Used in Dentifrice Intervention3: Potassium Nitrate: 5

Sponsors

Self Funded
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1. The individuals aged 18 to 75 years with a history of dentinal hypersensitivity. 2. Subjects with at least 20 natural permanent teeth and at least two teeth with a VAS score of >= 4.

Exclusion criteria

Exclusion criteria: 1. Teeth with caries, defective restorations, chipped teeth, deep periodontal pockets, periodontal surgery within the previous six months. 2. Subjects with orthodontic appliances or bridge work that would interfere with evaluation will be excluded. 3. Subjects will also be excluded if there was presence of occlusal overload or occlusal adjustment recently made in the tooth to be studied. 4. Subjects who had undertaken treatment with any product that could influence the dentinal hypersensitivity of the patient in the 30 days prior to baseline will be excluded. 5. Subjects will also be excluded if they were allergic to ingredients used in the study or exhibited any gross oral pathology, eating disorders, chronic diseases, pregnancy and lactation. 6. Medically compromised patients. 7. Poor oral hygiene and to failure to comply with protocol.

Design outcomes

Primary

MeasureTime frame
1. Clinical assessment: To measure the visual analogue scale score for Dentinal hypersensitivity in all three groups 2. Biochemical: pH and Buffering capacity of saliva in all three groups.Timepoint: base line, 6 weeks, 12 weeks

Secondary

MeasureTime frame
nilTimepoint: nil

Countries

India

Contacts

Public ContactDEEPTHI ATHULURU

NARAYANA DENTAL COLLEGE AND HOSPITAL

dr.chandu@gmail.com9444987949

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026