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EFFECT OF DEXMEDETOMIDINE ON HEART RATE AND BLOOD PRESSURE RESPONSES TO DOUBLE LUMEN TUBE INSERTION UNDER GENERAL ANAESTHESIA

EFFECT OF PROPHYLACTIC DEXMEDETOMIDINE ON HAEMODYNAMIC RESPONSES TO DOUBLE LUMEN TUBE INTUBATION UNDER GENERAL ANAESTHESIA

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/08/006066
Enrollment
50
Registered
2015-08-03
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA physical status I-II, Age 18â??65 years undergoing scheduled thoracic surgery requiring double lumen tube for isolation of lungs

Interventions

Intervention1: dexmedetomidine: 0.7mcg/kg dexmedetomidine in 0.9% NaCl- 20â??mL in 10 minutes followed by fentanyl 2 mcg/kg,propofol 1.5-2 mg/kg and rocuronium 0.8-1 mg/kg Control Intervention1: NaC

Sponsors

Tata Memorial Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: ASA physical status I-II, Age 18â??65 years undergoing scheduled thoracic surgery requiring double lumen tube for isolation of lungs

Exclusion criteria

Exclusion criteria: H/O allergy to study drug,ASA III and IV,Mallampati Grade 3 and 4,Patient with Heart Block /Pacemaker /HR 1.5),Liver impairment,Poorly controlled hypertension,Patient refusal,Pregnancy,

Design outcomes

Primary

MeasureTime frame
Changes in hemodynamic parameters- HR,SBP,DBP, MAP,RPP will be observedTimepoint: Changes in hemodynamic parameters- HR,SBP,DBP, MAP,RPP will be observed at the following time intervals Preanaesthetic Checkup. Baseline â?? on OT table. Beginning and end of infusion. Before intubation(3 mins after anaesthetic induction), during intubation at 0 mins and after one minute intervals till 10 mins of intubation.

Secondary

MeasureTime frame
Adverse effects- hypotension, hypertension, bradycardia, airway obstruction will be observedTimepoint: Adverse effects like hypotension, hypertension, bradycardia, airway obstruction will be observed during the procedure

Countries

India

Contacts

Public ContactDr Malini Joshi

Tata Memorial Hospital

drraghavendrak@gmail.com9930339575

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026