Health Condition 1: null- Patients suffering from knee osteoarthritis.
Conditions
Interventions
Intervention1: Capsule Longvida: One 400 mg capsule once a day with water before meal orally for 90 days.
Control Intervention1: Capsule Ibuprofen: One 400 mg capsule once a day with water before meal
Sponsors
Pharmanza Herbal PvtLtd
Eligibility
Inclusion criteria
Inclusion criteria: Patients of either sex, 40 to 60 years of age diagnosed with osteoarthritis of the knee based on the American College of Rheumatology (ACR)criteria and patient willing to comply with study procedures and requirements.
Exclusion criteria
Exclusion criteria: 1.Patients with congenital arthropathy, rheumatoid arthritis, active gout, other type of arthritis with/without inflammation e.g. septic , fibromyalgia or collagen vascular disease 2.Patients with known history of coagulopathies 3.Osteoarthritis of any other joint except knee 4.Patients with history of major trauma or surgery in the knee joint 5.Patients with uncontrolled diabetes and hypertension 6.Body mass index (BMI) >40 kg/m2. 7.Patients with any severe cardiac, renal and hepatic disease 8.Pregnant and lactating women 9.Patients who participated in any clinical trial within 30 days before enrollment into the study
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The primary outcomes of the study will be measured in terms of clinical signs by Local examination, Goniometry, WOMAC score and Visual analogue scale. Timepoint: After every 15 days | — |
Secondary
| Measure | Time frame |
|---|---|
| The secondary outcome will be measured by biochemical profiling of Inflammatory and degenerative markers.Timepoint: Inflammatory marker - Day0, Day7 and day 90 Degenerative marker - Day 0 and Day 90 | — |
Countries
India
Contacts
Public ContactDr Supriya Bhalerao
Interactive Research School for Health Affairs Bharati Vidyapeeth Deemed University
Outcome results
None listed