Health Condition 1: null- ASA Class 1&2 patients scheduled for elective ENT surgeries.
Conditions
Interventions
Intervention1: GROUP D (DEXMEDITOMIDINE): Bolus dose of dexmeditomidine 1 micrograms/kg body weight i.v over 10 minutes followed by infusion of dexmeditomidine 0.6 micrograms/kg/hr.
Control Interventi
Sponsors
Dr Rohit Kaushikbhai Patel
Eligibility
Inclusion criteria
Inclusion criteria: A) ASA class 1&2 scheduled for elective surgeries. B) age between 18 & 60 years. C) no history of alcohol or drug abuse. D) not received any opioid analgesic or alpha 2 agonist 24 hours prior to surgery.
Exclusion criteria
Exclusion criteria: A)history of allergy to alpha agonist or sulpha drug. B)pregnant, lactating mothers and morbidly obese patients. C)heart block. D)presence of clinically significant neurologic, cardiac,renal,hepatic,gastrointestinal endocrine disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| To Study and compare the effects of dexmedetomidine with fentanyl for 1) The sympatholytic effects & intraoperative hemodynamics. 2) Reduction in intraoperative propofol requirement. 3) The recovery variables.Timepoint: Heamodynamics parameters observed intraoperatively and recovery variables during extubation. | — |
Secondary
| Measure | Time frame |
|---|---|
| To compare analgesic sparing effects and postoperative nausea and vomiting of dexmedetomidine with fentanyl.Timepoint: Secondary outcome observed after extubation for one hour. | — |
Countries
India
Contacts
Public ContactDr Rohit kaushikbhai patel
Government medical college surat
Outcome results
None listed