None listed
Conditions
Interventions
Intervention1: Cholecalciferol granules: Each satchet containing 60,000 IU of cholecalciferol orally , 1 per week for 6 weeks and then 1 monthly for 4 months
Control Intervention1: Placebo: One satche
Sponsors
UCMS and GTB Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Primigravida at 16-24 weeks of gestation (by L.M.P. Method)at the time of enrollment
Exclusion criteria
Exclusion criteria: 1. Age 30 yrs 2. Multiple pregnancy 3. Extreme malnutrition (BMI >35 & 4. Patients having B.P. Systolic >130 or Diastolic >90 mmHg 5. Patients presenting with preeclampsia,antepartum haemorrhage 6. History of past chronic medical illnesses & drug history
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Comparison between the groups for the incidences of I) Adverse maternal outcomes: - Gestational Hypertension - Preeclampsia - Spontaneous preterm rupture of membranes II) Adverse neonatal outcomes: - Preterm birth - Small for gestational age newborn III) 25(OH) D levels of those who develop complications to those who do not develop complications Timepoint: at the time of delivery | — |
Secondary
| Measure | Time frame |
|---|---|
| (a) Reduction in incidence of 1 - Maternal deaths 2- Maternal admissions to ICU 3 - Still Birth 4 - Early neonatal deaths ( 7days ) (b) Improvement in 1 - Apgar score at 1 min and 5 min of birth Timepoint: within 7 days of delivery | — |
Countries
India
Contacts
Public ContactDr Pankila Mittal
UCMS & GTB Hospital
Outcome results
None listed