Skip to content

A pilot study to determine the use of Sertraline in patients with hypertension and anxiety disorder.

The Effects of Low Dose Sertraline on Blood Pressure in Patients with Hypertension and Panic Disorder: A Pilot Study

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2015/07/006028
Enrollment
80
Registered
2015-07-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients with panic disorder and hypertension.

Interventions

None listed

Sponsors

King Georges Medical University Department of Geriatric Mental health
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: -Diagnosed panic disorder/panic attacks/generalised anxiety disorder who are otherwise suitable for SSRI therapy -Diagnosed hypertension and on at least one medication for hypertension -Compliant patient with access and availability to attend at least three (3) additional hospital sessions

Exclusion criteria

Exclusion criteria: -Cardiovascular Instability, such as history of myocardial infarction, arrhythmias or stroke -Hypotension -Currently active malignancy -Pregnancy or Breast-feeding -Involvement in another clinical trial -Current or recent (within 90 days) DSM-IV Major Depressive Disorder. -Hypersensitivity to, or currently using, any serotonergic medicines, such as tryptophan, tramadol etc -Contra-indication to serotonergic medicines

Design outcomes

Secondary

MeasureTime frame
Whether Sertraline is successful as adjunctive therapy to standard antihypertensive medications in lowering blood pressure in those with anxiety/panic disorders. Timepoint: 12 months

Primary

MeasureTime frame
Change in the scores for panic/anxiety disorder over 4 week period. Timepoint: 12 months

Countries

Australia, India

Contacts

Public ContactDr Shrikant Srivastava

King Georges Medical University

shrikantsrivastava@kgmcindia.edu8604623243

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026