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To identify markers of cardiovascular disease in diabetic nephropathy patients

A Comparative and Correlative Study of Trace Elements, Oxidative Stress Indices and Renal Function parameters as Biomarkers of Cardiovascular Disease in Type 2 Diabetic Nephropathy Patients

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2015/07/005978
Enrollment
168
Registered
2015-07-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Type 2 Diabetes Mellitus and Cardiovascular Disease

Interventions

None listed

Sponsors

Shaina Pinto
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: The subjects for the study will be selected on the following basis - • Group I â??Euglycemic subjects with â?? Fasting Blood Glucose(FBG) 70-110mg/dl, Post Prandial blood Glucose (PPBG) • Group II â?? T2DM patients (recently diagnosed) with â?? FBG >= 126gm/dl, PPG >= 200gms/dl HbA IC >=6.5% • Group III- T2DN Patients without Cardiovascular Disease (CVD)with â?? FBG >= 126gm/dl, PPG >= 200gms/dl , HbA IC >=6.5% , Urine Microalbumin>= 30mg/day or >= 30mg / g Creatinine • Group IV- T2DN with CVD - FBG >= 126gm/dl, PPG >= 200gms/dl HbA IC >=6.5%, Urine Microalbumin >= 30mg/day or >= 20mg/g Creatinine, And clinically diagnosed with Cardiovascular Disease

Exclusion criteria

Exclusion criteria: 1) Patients with systemic illness (liver disease, polycystic ovary syndrome ,cerebrovascular accidents, chronic infections and inflammatory diseases, autoimmune disorders, non-diabetic nephropathy, psychiatric patients, cancer). 2) Patients taking supplements of antioxidants, vitamins and Minerals. 3) Pregnant and breast feeding women 4) Patients with any Trauma, Major surgery and GI disorders 5) Non diabetic cardiovascular diseases and non diabetic renal failure

Design outcomes

Primary

MeasureTime frame
Trace elements and Oxidative stress indices act as bio markers of cardiovascular disease in Type 2 diabetic Nephropathy Ptients with Nephropathy.Timepoint: 3 years

Secondary

MeasureTime frame
The trace element status in type 2 diabetic nephropathy patients will suggest the incidence of Cardiovascular disease riskTimepoint: 3 years

Countries

India

Contacts

Public ContactShaina pinto

Father Muller Medical College , Mangalore

shainakiran@yahoo.com9845644496

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026