Health Condition 1: null- Patients with histological confirmation of diagnosis of Non small cell lung cancer (NSCLC)
Conditions
Interventions
Intervention1: NIL: NIL
Intervention2: NIL: NIL
Sponsors
Tata Memorial Centre
Eligibility
Inclusion criteria
Inclusion criteria: 1)Treatment cases with histological confirmation of diagnosis of Non small cell lung cancer (NSCLC). 2)Non metastatic early- stage operable lung cancer size 3)PET-CT scan performed within 8 wks before surgical resection of tumour. 4)Surgical resection either a lobectomy or pneumenectomy
Exclusion criteria
Exclusion criteria: 1)Patients who received chemotherapy prior to surgery. 2)Positive margins post resection as on histopathology report. 3)PETCT performed 8 weeks prior to resection 4)Previously treated cases of cancer.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| 1.To determine the cut-off standardized uptake value (SUV) on 18F fluoro-2-deoxy-glucose (FDG) positron emission tomography/computed tomography (FDG-PET/CT) images that correlates best with pathologic gross tumor volume (GTVpath) for nonâ??small-cell lung cancer (NSCLC) by various (semi) automated delineation methods, to compare CT based visual assessment with pathology.Timepoint: NIL | — |
Secondary
| Measure | Time frame |
|---|---|
| 1 compare differences in tumor volume as delineated by various semiautomated methods and corresponding data obtained on pathological specimen and to quantify the magnitude of difference 2 Determine interobserver variability between observers in auto-contourâ??based delineation in the delineation of the GTV and manual PET-CTâ??based delineation in patients with untreated NSCLC. 3.Validation of the obtained results of one best fit method on subsequent 15 patients in validation group Timepoint: NIL | — |
Countries
India
Contacts
Public ContactDr Jai Prakash Agarwal
Tata Memorial Hospital
Outcome results
None listed