Health Condition 1: null- COPD with pulmonary hypertension
Conditions
Interventions
Intervention1: Sildenafil: The choice for an agent will depend on the patients status, desire, co-morbidities and financial status (unless sponsored) along with the Physicians prerogative for any part
to start it will be a low dose and it will be raised slowly to a maximum level as per the decision of the Physician.
The patients will be evaluated after 3 months of the initiation of treatment. Once
Sponsors
Institute of Pulmocare and Research
Institute of Pulmocare and Research
Eligibility
Inclusion criteria
Inclusion criteria: a) These patients shall have to be on optimal standard mamagement of COPD and existing co-morbid conditions.(The management of COPD should include standard pharmacotherapy as per guideline, logistically best possible education and training for self managed rehabilitation and home oxygen therapy as and when indicated). b) A proper written informed consent will be taken before including the patients in the study.
Exclusion criteria
Exclusion criteria: a) Patients unwilling to give proper written informed consent. b) Patients with severe co-morbid states affecting the quality of life. c) Very advanced COPD with inability to follow up or perform spirometry. d) History of exacerbation in the preceding six weeks. e) Patients with suspected OSA, ILD, left heart disease and pulmonary embolism (radiological suspicion for ILD, clinical suspicion of OSA from snoring, high BMI, excessive day time somnolence, observed apneas, and / or other features suggesting SDB). f) Patients with clinico-radio-echocardiographic suggestions of pulmonary embolism and echocardiography showing the presence of any significant left heart disease. g) Patients with known intolerance of sildenafil
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| a) To define PH in COPD patients on a composite clinico-radio-echocardiographic method. b) To look for the change in the quality of life through the use of CAT (COPD assessment test)scoring.Timepoint: Nil | — |
Secondary
| Measure | Time frame |
|---|---|
| NilTimepoint: Nil | — |
Countries
India
Contacts
Public ContactDr Parthasarathi Bhattacharyya
Institute of Pulmocare and Research
Outcome results
None listed