A clinical trial to compare the effects of four drugs,oxytocin,misoprostol,15-methylprostaglandinF2alpha and methylergometrine in active management of third stage of labor.

Efficacy of oxytocin, misoprostol, 15-methylprostaglandinF2alpha and methylergometrine in active management of third stage of labor.

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2015/06/005918

Enrollment

1000

Registered

2015-06-16

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Labor

Interventions

Intervention1: Group A: Injection 10 International Units (I.U) oxytocin intramuscular at the time of delivery of baby Intervention2: Group A: Injection Oxytocin 10 International Units (I.U) intramusc

Eligibility

Inclusion criteria

Inclusion criteria: All non-high risk women at term pregnancy (37 to 40 weeks of gestation) who delivered vaginally. Ready to give written and informed consent

Exclusion criteria

Exclusion criteria: Placental disorders-abruption placentae/ marginal placenta previa/low lying placenta. malpresentation, instrumental delivery,grand multipara,prvious uterine scar,rh negative pregnancy,liquor abnormalities/chorioamnionitis,coagulation disorders,medical disorders-anaemia/diabetes/hypertension/heart disease asthma , epilepsy.

Design outcomes

Primary

Measure	Time frame
1. To measure amount of blood lossTimepoint: 1. At the time of blood loss more than 500 ml	—

Secondary

Measure	Time frame
1.Duration of third stage of labor 2.Change in hematocrit from predelivery to 24 hour postpartum 3.Need for administration of other uterotonics and blood transfusion. 4.Side effects and complications within 24 hour.Timepoint: 1.Duration of third stage more than 6 min 2.Fall in hematocrit 3.Additional use of other uterotonics. 4. Side effects like nausea, hypertension, shivering,diarrhea.	—

Countries

India

Contacts

Public ContactDr Priyanka Thakur Dr Latika Sahu

Maulana Azad Medical College

latikasahu@gmail.com9968604400

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026