None listed
Conditions
Interventions
Intervention1: Biofortified wheat flour with 60 ppm zinc: chapathi made of biofortified wheat flour for lunch (1 meal/day) for 6 months.
Intervention2: Regular fortified wheat flour with 60 ppm zinc:
Sponsors
ETH Eidgenossische Technische Hochschule Zurich
Eligibility
Inclusion criteria
Inclusion criteria: zinc deficient otherwise healthy Indian school children
Exclusion criteria
Exclusion criteria: 1. Severe anemia (Hb 2. Consumption of a supplement or dietary supplement containing Zn. 3. Use of drugs that affect the metabolism of Zn, including reducing absorption or increasing excretion; for example tuberculosis medications (ethambutal and isoniazides), drugs used as treatment for entamoeba hystolica (diiodohydroxyquin), drugs that reduce stomach acidity (H2 blockers and proton pump inhibitory), antidepressants (nialamide and isocarboxazid), anti-inflammatory drugs (corticosteroids), diuretics (thiazides), aspirin, penicillamine and alcohol. 4. Suffering from a chronic disease affecting the metabolism of Zn, such as kidney disease or chronic gastrointestinal problems, as for example enter colitis, ulcers and other diseases disturbing the absorption of micro nutrients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Plasma zinc status, C reactive proteins, alpha 1- acid glycoprotein,Timepoint: Baseline Mid point ( 1- 5 months) endline(6 months) Followup (8 months) | — |
Secondary
| Measure | Time frame |
|---|---|
| Hemoglobin, plasma ferritinTimepoint: Baseline Mid point ( 1- 5 months) endline(6 months) Followup (8 months) | — |
Countries
India
Contacts
Public ContactDr Anura Kurpad
St. Johns Research Institute
Outcome results
None listed