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A clinical trial to study two drugs dexmedetomedine and ketamine in small doses in removing procedural discomfort during spinal anaesthesia

Comparison of efficacy of dexmedetomedine and subanaesthetic dose of ketamine in allaying procedural discomfort during establishment of subarachnoid block: A randomized trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/06/005888
Enrollment
60
Registered
2015-06-05
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- American society of anaesthesiologists class 1

Interventions

Intervention1: dexmedetomedine: inj dexmedetomedine 1mcg per kg intravenously in 100 ml Normal saline over 10 minutes(once only) Control Intervention1: dexmedetomedine ketamine: dexmedetomedine 1mcg p

Sponsors

Mahatma Gandhi medical college and research institute
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Willingness. ASA 1 & 2 physical status. Age 18 to 50 years.

Exclusion criteria

Exclusion criteria: Allergic to drugs used. Psychiatric disorder. Patients on beta blocker therapy. Contraindicated to SAB.

Design outcomes

Primary

MeasureTime frame
1. Degree of sedation 2. Ease of positioning 3. Prick response 4.Time interval between study drug injection and response to verbal commands 5. Recall of procedure 6. Patient satisfaction Timepoint: 1. during subarachnoid block look for prick response 2. level of sedation while patient is positioned for subarachnoid block 3. recall of spinal procedure at the end of surgery 4. verbal response time after sedation 5. satisfaction at the end of surgery 6. ease of positioning after Subarachnoid block

Secondary

MeasureTime frame
1. complications 2. hemodynamic variation from drug administraion to patient positioning after subarachnoid blockTimepoint: complications during the procedure hemodynamic variations from drug administration to patient position after subarachnoid block

Countries

India

Contacts

Public ContactHemanth Kumar

MAHATMA GANDHI MEDICAL COLLEGE AND RESEARCH INSTITUTE

drvrhk@gmail.com9003550553

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026