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use of midazolam with lignocaine for nerve block in forearm and hand surgeries for postoperative pain relief

A COMPARATIVE STUDY OF MIDAZOLAM IN TWO DIFFERENT DOSES AS AN ADJUNCT TO LIGNOCAINE FOR ULTRASOUND GUIDED SUPRACLAVICULAR BRACHIAL PLEXUS BLOCK A RANDOMISED CONTROLLED STUDY

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/06/005866
Enrollment
90
Registered
2015-06-04
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- patients undergoing orthopaedic upper extremity surgery

Interventions

Intervention1: midazolam in ultrasound guided supraclavicular brachial plexus block: Group L(control): 20 ml of 1.5% Lignocaine with adrenaline (1:200000) + 5 ml of Normal saline
Group M30 : 20 ml of 1.5% Lignocaine with adrenaline (1:200000) + midazolam 30 microgram/kg + Normal saline
Group M50 : 20 ml of 1.5% Lignocaine with adrenaline (1:200000) + 50 microgram/kg midazolam + Normal saline Intervention2: midazolam (50microgram/kg): Group 3 - 20 ml of 1.5% Lignocaine with adrenalin

Sponsors

Government of Himachal Pradesh
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1.Males and females between the age group 18-60 years. 2. ASA class I-II. 3. BMI 18.5-29.9. 4. Undergoing surgeries around elbow, forearm and hand.

Exclusion criteria

Exclusion criteria: 1.Patients refusal for block. 2.Patients having bleeding disorders. 3.Local infection at the site where needle for block is to be inserted. 4.Allergic to study drugs. 5.Patients of head injury, renal disease, liver disease and cardiac disease. 6.Patients in whom the block effect will be partial and will require supplementary anesthesia

Design outcomes

Primary

MeasureTime frame
â?¢To study and compare the duration of analgesia in three group of patients.Timepoint: duration of analgesia

Secondary

MeasureTime frame
â?¢To evaluate and compare the onset and duration of sensory and motor blockade with lignocaine with adrenaline (1: 200000) alone and with midazolam in two different doses. â?¢To find the optimal dose of midazolam as an adjunct for brachial plexus block and post-operative analgesia. â?¢To observe for side effects of midazolam, if any. Timepoint: .onset and duration of sensory and motor block

Countries

India

Contacts

Public ContactDr Versha Verma

Dr Rajendra Prasad Government Medical College

versha2u@yahoo.co.in09418152286

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026