Health Condition 1: null- neonatal seizures
Conditions
Interventions
Intervention1: Levetiracetam: In acute management of neonatal seizures to give 30 mg/kg/dose loading followed by 10 mg/kg/dose if seizure recurs and drug to be maintained at 20 mg/kg/day in BD dose
C
Sponsors
Dr Nikhil D Kulkarni
Eligibility
Inclusion criteria
Inclusion criteria: 1) > 1000 g birth weight and > 28 weeks gestation. 2)all term neonates
Exclusion criteria
Exclusion criteria: 1)hypoglycemic seizures 2)neonates treated with anticonvulsants prior to admission
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence of seizure and need for another anticonvulsant.Timepoint: Immediately on the day of seizure i.e. within 24 hours. | — |
Secondary
| Measure | Time frame |
|---|---|
| Monitoring of adverse drug reactions of each drug like Phenobarbitone toxicity, mortality and neurodevelopmental follow up in follow up clinic.Timepoint: After treatment of seizures within 7 days and on followup at 1 month, 3 months,6 months, 9 months, 12 months, 15 months, 18 months and 24 months. | — |
Countries
India
Contacts
Public ContactDr Nikhil D Kulkarni
St Johns Medical College and Hospital, Bangalore - 34
Outcome results
None listed