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Repair and Regeneration of Knee cartilage

Role of Autologous Chondrocyte Implantation in Chondral Defects of Knee Joint

Status
Active, not recruiting
Phases
Phase 1Phase 2
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/06/005841
Enrollment
50
Registered
2015-06-02
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: S870- Crushing injury of knee

Interventions

Intervention1: Autologous Chondrocyte Implantation: ACI comprises a series of procedures. First, cartilage sample is harvested arthroscopically from a non-weight bearing area of the affected knee join

Sponsors

Sri Sathya Sai Institute of Higher Learning
Lead Sponsor
Sri Sathya Sai Institute of Higher Medical Sciences prasanthigram
Collaborator

Eligibility

Inclusion criteria

Inclusion criteria: Patients with Femoral chondral defects in the age group of 18 to 50.

Exclusion criteria

Exclusion criteria: a)Patients below the age of 18 years and above the age of 50 years. b)Co-morbidities such as inflammatory arthritis and metabolic and endocrinal diseases. c)Patients unfit for surgical procedures from anaesthesia point of view. d)Patients with joint deformities in lower extremity.

Design outcomes

Primary

MeasureTime frame
.Improvement in pain scores .Improvement in range of motion of knee. . reaching the pre-injury level of activities. . prevention of the progression of the chondral defect to Osteoarthritis of knee.Timepoint: 3 months

Secondary

MeasureTime frame
. The patient may be able to participate in active sports and other activities . the procedure would help in the healing of the cartilage which is almost similar to hyaline cartilage present in non-injured knee.Timepoint: 2 years

Countries

India

Contacts

Public ContactPrakash kanchandani

Sri Sathya Sai Institute of Higher Medical Sciences, Prasanthigram

drprakashk@hotmail.com9652392745

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026