Extent of loss of consciousness and amount of drug required for it in adults

Minimum alveolar concentration of desflurane for maintaining BIS below 50

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2015/05/005823

Enrollment

Registered

2015-05-27

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA status I-II patients between the age group of 20-50 years undergoing elective surgery under general anesthesia

Interventions

Intervention1: BIS 50: End tidal desflurane concentration will be adjusted to 4.5% in first patient and maintained for 10minutes to ensure equilibration with cerebral anaesthetic partial pressure foll

Eligibility

Inclusion criteria

Inclusion criteria: undergoing elective surgery under general anesthesia

Exclusion criteria

Exclusion criteria: Abnormal ECG, cardiovascular or respiratory disease,regular use of hypnotic medications, drug or alcohol abuse

Design outcomes

Primary

Measure	Time frame
To determine MAC BIS50 value of desflurane in adult patients receiving general anesthesia .Timepoint: 6 values of BIS taken at 10-s intervals 10 minutes after intubation	—

Secondary

Measure	Time frame
nilTimepoint: nil	—

Countries

India

Contacts

Public ContactJeetinder kaur

post graduate institute of medical education and research,Chandigarh

jeet1516@gmail.com9914209510

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026