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To know appropriate sevoflurane concentration required for laryngeal mask airway placement in children

EC50 OF SEVOFLURANE FOR CLASSIC LARYNGEAL MASK AIRWAY INSERTION IN CHILDREN AT VARIOUS EQUILIBRATION TIME POINTS

Status
Active, not recruiting
Phases
Phase 3Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/05/005775
Enrollment
40
Registered
2015-05-14
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Children scheduled for undergoing cataract surgeries

Interventions

Intervention1: Group 2.5 minutes: 2.0% sevoflurane concentration will be administered for 2.5 minutes in first patient enrolled in the study.Then concentration will be increased of decreased by 0.2% f

Sponsors

Post Graduate Institute of Medical Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • Age 2-8 years • Either gender • ASA I and II • Children scheduled for undergoing cataract surgeries under general anaesthesia with CLMA

Exclusion criteria

Exclusion criteria: • Airway anomalies. • Anticipated difficult airway • Bronchial asthma • Known cardiac arrhythmia or congenital heart disease. • Mentally disabled, known case of autism, or developmental pervasive disorder. • Psychotropic medication use • Active upper respiratory tract infection • Patients receiving concurrent treatment with medication known to affect anesthetic requirements. • Weight of the patient exceeded 150% of the ideal weight. • The children who will need premedication after randomization will also be excluded.

Design outcomes

Primary

MeasureTime frame
EC50 of Sevoflurane for successful CLMATimepoint: 2.5 minutes and 5.0 minutes after predetermined ET sevoflurane is achieved

Secondary

MeasureTime frame
success rate of CLMA placement, attempts to successful placements, incidence of coughing, clenching of teeth, complications Timepoint: At or one minute after LMA

Countries

India

Contacts

Public ContactMANTOLIYA NIKHIL SHARMA

Post Graduate Institute of Medical Education and Research, Chandigarh

dr.mnikhilsharma@gmail.com9855780789

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026