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Efficacy and tolerability of imipramine, sertraline and des-venlafaxine in major depression

Comparative study of efficacy and tolerability of a tricylic antidepressant, a selective serotonin reuptake inhibitor and a serotonin norepinephrine reuptake inhibitor

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/05/005735
Enrollment
134
Registered
2015-05-01
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patient with depressive symptoms without any physical complications

Interventions

Control Intervention1: Sertraline: Dosage range 50 to 200mg a day in divided dose either once or twice a day by oral intake for six to nine months Control Intervention2: Des venlafaxine: Dosage range

Sponsors

Department of Psychiatry
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients in the age group of 18-65 years Patients with intelligent quotient ( IQ) within normal range Patients who were willing to participate in study

Exclusion criteria

Exclusion criteria: Patients of Bipolar depression Patients with Severe depressive disorders with psychotic symptoms Patients with co-morbid substance related disorders except nicotine & caffeine Patients with history of treatment resistant depression.

Design outcomes

Primary

MeasureTime frame
Hamilton Depression Rating Scale (HDRS) Hamilton anxiety rating scale clinical global impression scale Arizona sexual experience scale WHO quality of life scale(Hindi version) Zung self rating scaleTimepoint: Oct 2011

Secondary

MeasureTime frame
WHO quality of life Arizona sexual rating scaleTimepoint: WHO more than 100 Arizona sexual rating scale more than 20

Countries

India

Contacts

Public ContactDr Abhishek Kapoor

Government medical college hospital

drchavanbs@gmail.com9646121611

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026