Health Condition 1: null- ASAPS I or II, 20 - 65 years of either sex, of BMI less than or equal to 30 kg/m2, undergoing elective laparoscopic cholecystectomy under general anaesthesia
Conditions
Interventions
Intervention1: Pregabalin 150 mg: One hour before surgery, patients of study group were given oral pregabalin 150 mg
Sponsors
NIL
Eligibility
Inclusion criteria
Inclusion criteria: ASAPS I or II, of BMI less than or equal to 30 kg/m2, undergoing laparoscopic cholecystectomy under general anaesthesia
Exclusion criteria
Exclusion criteria: impaired kidney or liver functions, history of drug or alcohol abuse, expected difficult airway, history of chronic pain condition or daily intake of analgesics or corticosteroids, consumed gabapentin or pregabalin within 2 weeks prior to surgery, pregnant or lactating, any condition in with the study or rescue drug was contraindicated, ineligible to provide informed consent, any case converted to open cholecystectomy
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Intraoperative fentanyl requirements, Postoperative VAS pain scores at rest and during coughing, Time to requirement of first dose of postoperative analgesic (Tramadol 50- 100 mg. iv), Total postoperative tramadol requirement in 24 hour periodTimepoint: 0 min, 15 min, 30 min, 45 min, 1 hour, 2 hours, 4 hours, 6 hours, 8 hours, 10 hours, 12 hours, 14 hours, 16 hours, 18 hours, 20 hours, 22 hours, 24 hours | — |
Secondary
| Measure | Time frame |
|---|---|
| Level of perioperative anxiety and sedation, Induction dose of propofol, Time from cessation of inhalational anaesthetic to extubation, Incidence and severity of side effectsTimepoint: 0 min, 2 hours, 4 hours, 6 hours, 8 hours, 10 hours, 12 hours, 14 hours, 16 hours, 18 hours, 20 hours, 22 hours, 24 hours | — |
Countries
India
Contacts
Public ContactRoneeta Nandi
Yashoda Hospital, Somajiguda, Hyderabad
Outcome results
None listed