Health Condition 1: null- Term pregnant women
Conditions
Interventions
Intervention1: misoprostol: 25mcg orally every 2 hourly for a maximum of 6 doses.
Control Intervention1: misoprostol: 25mcg vaginally every 4 hourly for a maximum of 6 doses
Sponsors
Safdarjung Hospital
Eligibility
Inclusion criteria
Inclusion criteria: Only primiparous women with a live singleton pregnancy, period of gestation >37 weeks with obstetric or medical indications for induction, unfavourable cervix (Bishop score <= 6), cephalic presentation, reactive foetal heart rate pattern and intact membranes.
Exclusion criteria
Exclusion criteria: Previous uterine incision, allergy to prostaglandin administration, uterine contractions >= 3 in 10 minutes, maternal cardiac, asthma, renal, or hepatic disease, patients on magnesium sulphate therapy, patients with fetal growth restriction, oligohydramnios, leaking or bleeding per vaginum.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Misoprostol and oxytocin requirement, mode of delivery, labour complications like tachysystole, hyperstimulation, nonreassuring fetal heart rate (FHR), neonatal outcome including Apgar Score, nursery admission and acceptability of oral and vaginal route.Timepoint: At the time of first dose | — |
Primary
| Measure | Time frame |
|---|---|
| Interval from the first dose of misoprostol (induction) to vaginal delivery & the percentage of women delivering infants vaginally within 24 hours of induction.Timepoint: At the time of first dose | — |
Countries
India
Contacts
Public ContactDr Pratima Mittal
Safdarjung Hospital
Outcome results
None listed