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When to stop phototherapy in neonatal jaundice?

When to stop phototherapy in neonatal hyperbilirubinemia? - A Randomized Control Trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/04/005705
Enrollment
270
Registered
2015-04-20
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Neonates â?¥ 35 wks of gestation with birth weight more than 1800grams and received phototherapy as per American Aacademy of Pediatrics phototherapy charts for minimum duration of 24 hours.

Interventions

Intervention1: Group A: Phototherapy will be stopped immediately. TSB will be monitored after 12 hours. If the value of TSB is less than 12mg/dl, infant will be discharged home. Control Intervention1:

Sponsors

Fernandez Hospital
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: • Neonates >= 35 wks of gestation • Birth weight more than 1800grams • Received phototherapy as per AAP phototherapy charts for minimum duration of 24 hours.

Exclusion criteria

Exclusion criteria: Neonates with major congenital anomalies or underwent Exchange Transfusion

Design outcomes

Primary

MeasureTime frame
Rate of occurrence of hyperbilirubinemia as measured by the number of episodes of rebound hyperbilirubinemia/ total number of neonates enrolled. Rebound hyperbilirubinemia defined as TSB more than AAP age specific cut-off after stopping phototherapy or a rise of bilirubin greater than 0.5mg/hour.Timepoint: Will be followed till 48 hrs after stopping phototherapy

Secondary

MeasureTime frame
Duration of rebound phototherapy as measured in hoursTimepoint: Till discharge;Risk factors for developing rebound hyperbilirubinemiaTimepoint: Will be followed till 48 hrs after stopping phototherapy

Countries

India

Contacts

Public ContactDr Tejopratap Oleti

Fernandez Hospital

srinivasmurki2001@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026