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Effects of increased uric acid levels in pregnant patients

EFFECT OF MATERNAL HYPERURICEMIA ON POST-SPINAL HYPOTENSION AND UTERINE TONE IN NORMOTENSIVE PARTURIENTS UNDERGOING NON-ELECTIVE CESAREAN DELIVERY: A PROSPECTIVE OBSERVATIONAL STUDY

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
CTRI
Registry ID
CTRI/2015/04/005702
Enrollment
100
Registered
2015-04-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- This study will be conducted in normotensive parturients undergoing non-elective cesarean delivery under subarachnoid block

Interventions

Intervention1: nil: nil Control Intervention1: nil: nil

Sponsors

PGIMER
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: this prospective observational study will be conducted in 100 women with singleton pregnancy and normal blood pressure admitted to the institute and coming for non-elective cesarean section

Exclusion criteria

Exclusion criteria: exclusion criteria will be: - Pre-eclampsia or eclampsia - Placenta praevia - Previous cesarean delivery - Pre-existing heart disease, liver or renal disorders - Pre-existing or gestational diabetes mellitus - Presence of coagulation abnormalities - Presence of hyperuricaemia before pregnancy - Twin pregnancy - Patients undergoing cesarean delivery under general anaesthesia - Patients demanding labor analgesia

Design outcomes

Primary

MeasureTime frame
1 Incidence of post spinal hypotension as determined by total vasopressor used to keep systolic blood pressure more than 100 mmHg or to prevent a fall of more than 20% in MAP.Timepoint: Intraoperative period

Secondary

MeasureTime frame
2.Use of supplemental uterotonics required to maintain a tonus uterus. (Satisfactory(score more than 7) or unsatisfactory(score less than or equal to 7) as rated by the obstetrician using Duttaâ??s scoring system.) 3.Estimation of blood loss measured as a fall in the pre and postpartum haematocrit of more than 30%. 4.Short term neonatal outcome: Cord gases,1,5 minute Apgar scores, need for neonatal resuscitation. Timepoint: intraoperative and immediate postoperative period

Countries

India

Contacts

Public ContactDr Nidhi Bhatia

Department of Anesthesia and Intensive Care PGIMER Chandigarh

nidhi.bhatia75@gmail.com

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026