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Comparison of outcome using either intravenous or volatile anesthetic agents in intracranial aneurysm clipping surgery

Intravenous Versus Inhalational Anaesthesia Trial for Outcome following Intracranial Aneurysm Surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/04/005684
Enrollment
106
Registered
2015-04-08
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Patients who had suffered with aneurysmal subarachnoid hemorrhage undergoing surgical procedure of clipping aneurysm neck

Interventions

Intervention1: Desflurane: Relatively newer inhalational anaesthetic agent now being increasingly used for neurosurgeries due to its properties of rapid emergence. Many studies have demonstrated neuro

Sponsors

Post Graduate Institute of Medical Education and Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: 1) World federation of Neurosurgeons (WFNS) Grade I-II 2) American Society of Anaesthesiologists (ASA) Grade I-II.

Exclusion criteria

Exclusion criteria: 1) Any co morbidity other than hypertension or diabetes mellitus (i.e. Coronary artery Disease, COPD, Hepatic and Renal impairment) 2) Patients in sepsis

Design outcomes

Primary

MeasureTime frame
Glasgow outcome score at three months after dischargeTimepoint: Glasgow outcome score at three months after discharge

Secondary

MeasureTime frame
1)Modified Rankin Score at three months after discharge 2)Barthel Index at three months after discharge 3)Intraoperative haemodynamics 4)Intraoperative brain swelling 5)Perioperative biochemical markers of neuronal injury 6)Length of hospital stay Timepoint: 1.1) Three months after discharge 2.1) Three months after discharge 3.1)Preinduction 3.2)Post induction 3.3)Skin incision 3.4)Bone reflection 3.5)Dural reflection 3.6)Preclipping 3.7)During clipping 3.8)Post clipping 3.9)Dural closure 3.10)Skin closure 3.11)Post operative 1hr 4)Intraoperative Brain Relaxation 4.1)At dural opening 4.2)At dural closure 5.1)Perioperative 5.2)Intraoperative 5.3)Postoperative 6)Length of Hospital Stay

Countries

India

Contacts

Public ContactDr Hemant Bhagat

Post Graduate Institute of Medical Education and Research Chandigarh

hembhagat@rediffmail.com09216387387

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026