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Effect of Vitamin D supplementation on osteodystrophy in patients with chronic liver disease

Chronic liver disease: Status of micronutrients with special reference to vitamin D and its supplementation on hepatic osteodystrophy - A randomized controlled trial. - VITHOD

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/04/005674
Enrollment
150
Registered
2015-04-07
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Chronic liver disease

Interventions

Intervention1: Vitamin D and calcium: Cholecalciferol sachet orally (60,000 IU D3/week for first 8 weeks followed by 60,000 IU/month for 10 months along with two oral tablets of calcium carbonate (eac

Sponsors

Indian Council of Medical Research
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: All the consecutive patients with CLD (irrespective of the etiology and the disease severity) having vitamin D deficiency along with hepatic osteodystrophy would be enrolled

Exclusion criteria

Exclusion criteria: 1.Patients undergoing recent contrast study or nuclear medicine test. 2.Pregnant or lactating women 3.Patients with related thyroid, parathyroid disease, cushingâ??s syndrome, diabetes, malignancies, cardiovascular, pulmonary, and renal disease. 4.Patients with a history of immobilization in the past, known cases of osteoporosis on anti-osteoporotic drugs 5.Women with surgical menopause 6.Patients receiving calcium and vitamin D supplementation for 7.Patients receiving medications like steroids, HRT, calcitonin, bisphosphonates, anti-coagulants, anticonvulsants, thyroxine, antiepileptics, interferon, immunosuppressive agents, cholestryamine. 8.Patients with hemachromatosis and Wilsonâ??s disease 9.Patients who refuse to participate in the study

Design outcomes

Primary

MeasureTime frame
Change in level of vitamin D and Bone Mineral Density Timepoint: Baseline and 1 Year

Secondary

MeasureTime frame
NILTimepoint: NIL

Countries

India

Contacts

Public ContactProf Anoop Saraya

AIIMS,INDIA

ansaraya@yahoo.com011-26593294

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026