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comparing anesthesia of head with the drug labetalol for blood pressure changes

Comparison of Labetalol and Bupivacaine scalp block on the hemodynamic and entropy changes following skull pin application â?? A randomized clinical trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
CTRI
Registry ID
CTRI/2015/03/005635
Enrollment
66
Registered
2015-03-16
Start date
Unknown
Completion date
Unknown
Last updated
2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- ASA 1 AND 2

Interventions

Intervention1: INTRAVENOUS LABETALOL WILL BE GIVEN BEFORE LARYNGOSCOPY: GROUP L will receive Intravenous labetalol 0.25 mg/kg Control Intervention1: scalp nerve block to block all the nerves supplying

Sponsors

nil
Lead Sponsor

Eligibility

Inclusion criteria

Inclusion criteria: Patients aged 18 to 60 years, with ASA physical status 1 and 2, undergoing elective neurosurgical procedure under general anaesthesia and requiring application of skull pins were included in the study

Exclusion criteria

Exclusion criteria: Hypertensives, patients undergoing emergency surgery, intracranial aneurysm surgery, those having significant cardiac, pulmonary, renal or hepatic disease, those having contraindication to beta blockers, or taking treatment that can affect hemodynamic parameters were excluded

Design outcomes

Primary

MeasureTime frame
we designed this study to compare the efficacy of intravenous labetalol and bupivacaine scalp block on the hemodynamic changesTimepoint: at 30,60 90 120 180 300 seconds following skull pin application—

Secondary

MeasureTime frame
entropy changesTimepoint: at 30,60 90 120 180 300 seconds following skull pin application—

Countries

India

Contacts

Public ContactDr Prasanna Bidkar

JIPMER

drprasannabidkar@gmail.com919442706168

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026