Health Condition 1: null- Schizophrenia
Conditions
Interventions
Intervention1: Active high frequency rTMS to cerebellar vermis: A Magstim Rapid® device (MAGSTIM Ltd., Whitland, Wales) and an double angled cone cerebellar coil were utilized in the delivery of rTMS
Sponsors
Central Institute of Psychiatry
Eligibility
Inclusion criteria
Inclusion criteria: 1. Diagnosis of Schizophrenia (F20.0-F20.9) according to ICD-10-DCR 2. Patients on a stable dose of antipsychotic medication 3. Patients of either sex aged between 18-60 years. 4. Right handed, normotensive patients. 5. Patients giving written informed consent. 6. Screened eligible for rTMS.
Exclusion criteria
Exclusion criteria: 1. Current neurological or any comorbid psychiatric disorders. 2. History of substance abuse (Except nicotine and caffeine) in the past one month. 3. History of epilepsy, significant head injury or any neurosurgical procedure. 4. Subjects with cardiac pacemakers or other metal parts in the body. 5. Subjects who have received ECT in past 6 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Composite positive and negative symptoms assessed using the Positive and Negative Syndrome Scale (PANSS)Timepoint: Baseline, after last session and at 4 weeks (2 weeks post-rTMS) | — |
Secondary
| Measure | Time frame |
|---|---|
| Depressive symptoms using the Calgary Depression Scale for Schizophrenia (CDSS) and extrapyramidal side effects using Simpson-Angus Extrapyramidal Side Effects ScaleTimepoint: Baseline, after last session and at 4 weeks (2 weeks post-rTMS) | — |
Countries
India
Contacts
Public ContactVinod Kumar Sinha
Central Institute of Psychiatry
Outcome results
None listed