A clinical study of Vranari Guggulu and Vrana lepa in the management of Diabetic Foot Ulcer

A Clinical Study of the effect and validation of Vranari Guggulu and Karanjadi Vranalepa in the management of Madhumehajanya Vrana (Diabetic Foot Ulcer)

Status

Recruiting

Phases

Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2015/02/005586

Enrollment

100

Registered

2015-02-26

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Diabetic Foot Ulcer

Interventions

Intervention1: Vranari Guggulu and Karanjadi Vranalepa: Vranari Guggulu 500 mg bid with water internally and Karanjadi Vranalepa as external application for 45 days Control Intervention1: Kanchanara G

Eligibility

Inclusion criteria

Inclusion criteria: 1.Patients of both sexes between the age group of 18-60 yrs. 2.Type I and II DM 3.Clinically Diagnosed as Diabetic Foot Ulcer 4.Target ulcer duration more than 30 days

Exclusion criteria

Exclusion criteria: 1.H/o Infectious and systemic diseases 2.Ulcer on heel 3.Ulcer with exposed bone and tendon 4.Immune deficiency 5.Coagulation disorders 6.Cellulitis 7.Gangrene 8.Presence of underlying Osteomyelitis 9.Pregnant women 10.Malignancies

Design outcomes

Primary

Measure	Time frame
Mean percentage change in wound area,pain Recognized clinical prognostic factors like reduction in wound area and depth and wound healing Proportion of patients with complete wound closureTimepoint: Treatment period : 45 days Assessment in every week Active follow up : 45 days	—

Secondary

Measure	Time frame
Improve general condition of the patient wound healingTimepoint: Treatment period : 45 days Assessment in every week Active follow up : 45 days	—

Countries

India

Contacts

Public ContactDr Chadalawada Venkata Siva Koteswara Rao

Dr. NTR Health University, Andhra Pradesh

ayurdoctor007@gmail.com9441072007

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026