Study to treat patients with knee defects using adult stem cells

A Pilot Study on Autologous Chondrocyte Implantation - ACI

Status

Active, not recruiting

Phases

Phase 1Phase 2

Study type

Interventional

Source

CTRI

Registry ID

CTRI/2015/02/005568

Enrollment

100

Registered

2015-02-24

Start date

Unknown

Completion date

Unknown

Last updated

2021-11-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Health Condition 1: null- Focal chondral defects in the knee

Interventions

Intervention1: Open label,Single arm: 1 million cells at site of Knee injury single dose Control Intervention1: Not applicable: Not applicable

Eligibility

Inclusion criteria

Inclusion criteria: History of Grade III & IV defect on the medial or lateral femoral condyle or troclea,Failed prior treatment to articular defects of the knee

Exclusion criteria

Exclusion criteria: Alcohol or drug abuse during last 3 years,Inflammatory joint disease,Serious illness and infective etiology

Design outcomes

Primary

Measure	Time frame
Treatment efficacy from the baseline in KOOS scoreTimepoint: 36 months	—

Secondary

Measure	Time frame
Change status from baseline in quality of life by way of OA scoreTimepoint: 3 years	—

Countries

India

Contacts

Public ContactDr J V S Vidyasagar

Global Hospitals

lkiran@globalhospitalsindia.com9848112342

Outcome results

None listed

Source: CTRI (via WHO ICTRP) · Data processed: Feb 4, 2026